Microdialysis probes cma

Microdialysis probes cma. 28 mm Outer Diameter 1 and 2 mm Length Probe Shaft Material Stainless-steel 0. , 2014. of 3: 8309661 The CMA 8 Microdialysis Probe is ideal for use in small areas of the brain or spinal cord of small animals. Francisco, M. 15. Pin style probes have a membrane located at the distal end of a supporting cannula. 5 mL 830 9022 Microsyringe 5 mL 340 8300 Syringe Clip, small 1-2. 3791/64531. Study of captopril pharmacokinetics in rabbit blood with microdialysis based on online generated Au nanoclusters and pepsin–captopril interaction in luminol chemiluminescence. $21. The CMA 142 Microfraction Collector is a unique, stand-alone instrument dedicated to microdialysis sampling. 61465–61475. Quality & Expertise. RELATED PRODUCTS Columns Thermo Scientific Interchim Machery-Nagel Tosoh Bioscience Shodex Column and Four infusion pumps (CMA 4004; CMA Microdialysis AB, Solna, Sweden) were equipped with a total of 16 micro-syringes (2. 5 cm deep to the inner table of the skull, and typically in the white matter. The perfusion fluid enters the membrane space through two holes in the inner cannula and flows into the shaft to the outlet. A variety of probe types with more than twenty different membrane and shaft length combinations are available from CMA. Tailored for dialysis in peripheral tissues and blood vessels Inlet and outlet tubing is attached Soft, non-metallic construction Available membranes: PAES, 20 kDa MWCO or PES, 100 kDa Instruments for microdialysis studies in freely moving small conscious animals over long periods of time. ORDER INFORMATION Ref No. of 3: 8010431: View Price: CMA 12 Elite Probe, 2 mm membrane length, pkg. The FEP Tubing with a 0. Self-made assemblies are often less expensive then commercially available ones if an inexpensive source of labor (e. CMA 31 Microdialysis Probes . It causes less tissue damage than other probe types due to its The probes manufactured by CMA Microdialysis are warranted to be free from defects in material and workmanship for a period of two years from the manufacturing date if stored in the original Our Products. Compare. This setup allowed the simultaneous addition of substrate, dialysate collection and respiration CMA Microdialysis is a market leader for the development and distribution of full solutions for microdialysis research, including probes, pumps, fraction collectors and related accessories. Description Syringe Pumps CMA 8003100 CMA 402 Pump with Accessory Kit CMA 8003110 CMA 402 Pump CMA 400400 CMA 4004 Pump 70-4402 HAPC-2: Controller populated with 2 channel modules 70-4806 Connected to the syringes in the CMA 402 Syringe Pump and a Microdialysis probe, two different perfusion fluids can be combined, even gradually, without introducing air bubbles into the system. Run the pump to make sure that liquid leaves the tip of the syringe cannula. of 3: 8010434: View Price: CMA 12 HighCO Probe, 1 mm membrane length, pkg. The Split Tubing enables reuse of CMA 20 Custom Probes and Guides CMA Probe Selection; CMA Probe Sterilization; CMA Probe & Guide Reusability; Product. It causes less tissue damage than other probe types due to its small diameter. Other Harvard Bioscience Support Centers. Mount the microdialysis probe in the CMA 11 & 12 Probe/Guide Clip on the CMA/130 in vitro Stand. 2 µL Outlet Volume 2. US Office Harvard Apparatus The CMA 7 Microdialysis Probe is not intended for use in humans. se The CMA 20 Microdialysis Probe is designed for dialysis experiments in moving soft tissues such as muscle, heart, skin and adipose tissue, as well as in blood, vitreous fluid of the eye, etc. Flow rate range (0. 154–161. , 2003). of 3: 8010434: CMA 12 HighCO Probe, 1 mm membrane length, pkg. se CMA 8 Microdialysis Probe for CNS Studies. New. Fractions ranging from 1 to 50 µL can be collected from one or two microdialysis probes (1 x 20 or 2 x 10 samples respectively). Select between dual collection, 2x10, samples or single collection,1x20, samples. The stand includes three holders for 1. CMA 4004 Microdialysis Syringe Pump CMA 20 Microdialysis Probe – Publications - 3 33. of The CMA 31 Linear Microdialysis Probe is ideal for peripheral tissues such as skin, muscle, heart, adipose tissue, liver, eye, pancreas and other organs as well as tumors. CMA Microdialysis AB Head Office, Sweden Torshamnsgatan 30A, SE-164 40 Kista, Sweden Tel: +46 8 470 10 00 E 15. Recoveries of glucose, lactate, The Microdialysis probes designed to mimic a blood capillary have a semi-permeable membrane that, when perfused with a physiological salt solution, allows an exchange of compounds from an area of high concentration to an area of low concentration. The CMA 8 Microdialysis Probes are ideal for use in small areas of the brain or spinal cord of small animals. 34. The CMA 12 Microdialysis Probe is ideal for stereotaxic work in the The CMA 20 Microdialysis Probe is designed for dialysis experiments in moving soft tissues such as muscle, heart, skin and adipose tissue, as well as in blood, vitreous fluid of the eye, etc. 5 mm Available metal free The CMA 7 Microdialysis Probe is not intended for use in humans. Hurtado, F. A. 1. Optimized for CNS use Ideal for chronic implantation. 2 mm on center with a guide. All our efforts are focused in providing high quality solutions developed specifically for microdialysis applications and manufactured keeping in mind the highest Page 1 CMA 12 Elite Microdialysis Probe User’s Manual TECHNICAL INFORMATION Membrane Material Polyarylethersulfone (PAES) Molecular Cut-Off 20,000 Daltons Outer Diameter 0. Page 1 CMA 7 55 kDa & 2MDa Microdialysis Probe User’s Manual TECHNICAL INFORMATION Membrane Polyethersulfone (PES) Material 500kDa, 2MDa Molecular Cut-Off 0. A new opportunity to identify patterns of protein expression in a variety of tissue spaces and to evaluate potential useful biomarkers of disease (Alzheimer’s disease, stroke, cancer) • CNS and periphery microdialysis probes • Sampling Large molecules: proteins, cytokines, neuropeptides • 55kDa, 100kDa, 500kDa CMA Microdialysis only guarantees single usage of CMA 12 Microdialysis Probes. Published 2022 Sep 13. of 3: 8012424: View Price We here present the design of a probe assembly step by step which will enable researchers to build custom-made probes. As with the other models, the probe is of concentric construction, but is made completely from plastic materials. commercially produced microdialysis probe in the world, was probably the most significant microdialysis in neurobiological research. An extremely small plastic body, where the inlet and outlet tubing are directly mounted, makes this probe easy to implant and light for a small animal to carry. Influence of peptide transporter 2 (PEPT2) on the distribution Introduction Products CMA develops and produces a complete range of microdialysis products. All our efforts are focused in CMA 31 Microdialysis Probe – Publications - 1 PUBLICATIONS . A matching small and New CMA 7 microdialysis probes for large molecules are also now available with 500 kDa and 2 MDa cut-off, 0. Biochrom Support Center; DSI Support Center; HBIO Harvard Apparatus Support Center; KDS Support Center Superior Microdialysis Probes & Guides for Every Application. 6 – 2. The CMA Microdialysis is a market leader for the development and distribution of full solutions for microdialysis research, including probes, pumps, fraction collectors and related accessories. A representative proportion of molecules from the extracellular fluid is then carried to the probe outlet for Probe recoveries of substances with different molecular weight (ranging from 100 to 1600 Da) were compared for three different probes (CMA 12 Elite probe, custom-made 10 kDa and 30 kDa probes). All metal parts are treated to Microdialysis probes manufactured by CMA Microdialysis AB, Kista, Sweden. com Harvard Apparatus 84 October Hill Road Holliston, MA 01746 USA Phone Orders: 800-232-2380 • Fax: 508-429 CMA Microdialysis only guarantees single usage of CMA 30 Linear Microdialysis Probes. of 10 (for CMA 30 only) 8010464: View Price : ×. MBR microdialysis probes can be implanted as close as 2. com Harvard Apparatus 84 October Hill Road Holliston, MA 01746 USA Phone Orders: 800-232-2380 • Fax: 508-429 Buy and sell Microdialysis equipment including pumps, probes, tubing and more for sale. Connect a Tubing Adaptor to the blue inlet tubing of the microdialysis probe and Connected to the syringes in the CMA 402 Syringe Pump and a Microdialysis probe, two different perfusion fluids can be combined, even gradually, without introducing air bubbles into the system. Phone: +46 8 470 10 10 . CMA 142 Microfraction Collector 5. New CMA 11 microdialysis probe for large molecules are also now available with 500 kDa and 2 MDa cut-off, 0. The basic research portfolio includes a broad range of probes, pumps, fraction collectors and complete systems for research. The swivel brace holds a wire with a collar connector and two holders for 300 µl plastic vials. of 3: 8012421: View Price: CMA 7 500 kDa Microdialysis Probe, 2 mm membrane length, pkg. 6 µL 200 mm Outlet CMA Microdialysis is a market leader for the development and distribution of full solutions for microdialysis research, including probes, pumps, fraction collectors and related accessories. CMA Microdialysis probes. Email: cma@microdialysis. The small, light, and compact design makes the CMA 8 ideal for use in small areas of the brain or spinal cord. Including: Microdialysis CAD Software Ref. of 10: 3409500: View Price: Tubing Adapters for CMA Linear Microdialysys Probes, pkg. CMA Microdialysis offers custom-made probes and guides of specific materials and in various geometries for various organs and biological species. The Tubing Adaptors are used for connecting FEP Tubing to the microdialysis probe, swivel, liquid switch and syringes. , 2017. CMA Probe Selection Table of Content . Declarations of Conformity CMA Syringe pumps and Instruments; Probe Accessories. The swivel is mounted on the balancing arm allowing free movement of the animal. The guide cannula can be mounted to a stereotaxic instrument using a standard probe clip. K. Extremely small. 24 mm (6 kDa), 0. In general, the cutoff of the membrane should be at least 3-4 times the molecular weight of the molecule. Please follow this link for microdialysis probes and guides. Dall, C. There is also an option to collect samples into open vials. (A) CT; The ICP probe's thin shaft and bulbous end can be distinguished from the PbtO 2 probe's uniform shaft and tip. They are most often used for brain microdialysis, though they can also be used for vascular and other implants. 2 µl/100 mm length) is, together with the Tubing Adapters, ideal for use in microdialysis experiments. 6 μl/min versus 2. CMA 12 Elite Probe, 1 mm membrane length, pkg. CMA 30 Linear Microdialysis Probe, 4/pkg CMA 8010460 Tubing Adapter, 10/pkg CMA 3409500 Tubing Adapter for Linear Probe, 10/pkg CMA 8010464 FEP Tubing, 1m, 1/pkg CMA 3409501 Microdialysis probes manufactured by CMA Microdialysis AB, Kista, Sweden. All our efforts are focused on providing high quality The CMA 31 Linear Microdialysis Probe is ideal for peripheral tissues such as skin, muscle, heart, adipose tissue, liver, eye, pancreas and other organs as well as tumors. All our efforts are focused in providing high quality solutions developed specifically for microdialysis applications and manufactured keeping in mind the highest The CMA 12 Microdialysis Probe is ideal for stereotaxic work in the CNS of anesthetized or conscious animals. Chromatography; Sample Dialysis; Equilibrium Dialysis; CMA 402 Microdialysis Syringe Pump . 2. Probe Tubing; CMA Probe Clips; Pumps & Fraction Collectors. The new CMA 8 Microdialysis probe is optimized for in vivo microdialysis studies of the central nervous system. RSC Advances, 4(106), pp. Connect the desired length of tubing to the The CMA 120 can be used in combination with any one of the CMA microdialysis systems. 800 3110 . Once implanted, the probe sits tightly in the guide cannula´s capsule without the need for screwing or cementing. A semi-permeable membrane is glued between the tip of the inner steel cannnula and the outer steel shaft. 5 mL 340 8310 Syringe Clip, medium 2. Along the membrane, in this window, a thin part FEP Tubing allows safe connection of the CMA 11 and CMA 12 probes to pumps and fraction collectors. 26 mm (55 kDa) or CMA 7 500 kDa Microdialysis Probe, 1 mm membrane length, pkg. The cutoff of the membrane should be chosen based on the size and type of molecule being targeted. Microdialysis is a minimally-invasive sampling technique that is used for continuous measurement of free, unbound analyte concentrations in the extracellular fluid of virtually any tissue. CMA Microdialysis AB Head Office, Sweden Torshamnsgatan 30A, SE-164 40 Kista, Sweden Tel: +46 8 470 10 00 E-mail: cma@microdialysis. The probe is very thin, made with a unique patented design with a 10 mm membrane, 55,000 Daltons cut-off. Muscarinic receptor M4 positive allosteric modulators attenuate central effects of cocaine. FEP tubing is connected to the probe using tubing adaptors. There are issues that present as the cutoff increases, so it is wise to use the CMA Microdialysis probes. Only the gold filament at the end of the microdialysis catheter is visible. ) to assess their CMA 7 Custom Made Probe, pkg. neurotransmitter, hormones, glucose, etc. 0 μl/min), the method of microdialysis CMA 7 500 kDa Microdialysis Probe, 1 mm membrane length, pkg. US Office. se . of 4: New CMA 11 microdialysis probe for large molecules are also now available with 500 kDa and 2 MDa cut-off, 0. Instantly switch between syringes; No interruption of flow CMA Probe Shaft Clip Micro T Microdialysis CAD Software Ref. of 3: 8010433: CMA 12 Elite Probe, 4 mm membrane length, pkg. of 3: 8010397: View Price: CMA 20 Custom Made Probe, pkg. of 3: 8012424: View Price We studied the structure and function of a widely used, commercially available microdialysis probe (CMA/20), which has been used for protein microdialysis in a number of studies. 40 mm Diameter 14 mm Length Internal Volume 0. No. CMA Microdialysis is a market leader for the development and distribution of full solutions for microdialysis research, including probes, pumps, fraction collectors and related accessories. The probe consists of a tubing in which the middle part has a 10 mm window with a Cuprophane membrane, 6,000 Daltons cut off. CMA 130 in vitro stand (CMA, Harvard Apparatus, Holliston, MA, USA). D. 5 ml Eppendorf tubes and three probe clips. , students) is available. , 2006) versus handmade probes in the prior studies (Sam and Justice, 1996; Bungay et al. com Harvard Apparatus 84 October Hill Road Holliston, MA 01746 USA Phone Orders: 800-232-2380 • Fax: 508-429 CMA Microdialysis offers a complete range of microdialysis products for scientific research. Probes are commercially available from such suppliers as Applied Neuroscience, Bioanalytical Systems, CMA/Microdialysis, ESA, and Metallhantering AB, Bioanalytical Systems (see suppliers appendix). The CMA 12 Microdialysis Probe is ideal for stereotaxic work in the CNS of anesthetized or conscious animals. 1–20μl) (CMA, Harvard Apparatus, Holliston, MA, USA). Please follow this link for microdialysis probes and The CMA 4004 Touch Screen Syringe Pump is easy to use and can hold four syringes, providing very broad flow ranges rate suitable for microdialysis. This makes it possible to change different solutions instantaneously without any risk of introducing air bubbles into the microdialysis probe. applications, or need customizable probe sizes, our CMA and Harvard Apparatus brands offer a variety of instruments, including pump options, to help you optimize your set-ups for each study. CMA 120 Instrument Table CMA 7 Microdialysis Probe – Publications - 1 PUBLICATIONS . Can be mounted to a stereotaxic instrument using a standard Probe Clip. The probe is small and lighter than the CMA 12 probes allowing the use of 20 kDa and 100 kDa membranes in mice. CMA 7 Microdialysis Probe, 1 mm, 3/pkg CMA P000082 CMA 7 Microdialysis Probe, 2 mm, 3/pkg CMA P000083 CMA 7 Metal Free Probe, 1 mm, 3/pkg CMA 8010771 CMA 7 Metal Free Probe, 2 mm, 3/pkg CMA New CMA 7 microdialysis probes for large molecules are also now available with 500 kDa and 2 MDa cut-off, 0. Get high quality results with high quality probes! www. Our product line includes a broad range of microdialysis probes, pumps, fraction collectors and associated accessory products to assemble Custom Probes and Guides. An extremely small plastic body, where the inlet and outlet tubing are directly mounted, makes the probe The CMA 7 Microdialysis Probe is not intended for use in humans. The probes have elongated inlet/outlet tubing to keep fingers further away from fast, sharp mouse teeth when connecting CMA Microdialysis is a market leader for the development and distribution of full solutions for microdialysis research, including probes, pumps, fraction collectors and related accessories. 8. The CMA 402 is available in two different versions, one of which includes accessories such as vial holders and probe clips, allowing easier handling of the microdialysis probe. com CMA Microdialysis AB Headquarters: Box 2, SE-171 18 Solna, Sweden, Tel: +46 8 470 10 00 Fax: +46 8 470 10 50 E-mail: CMA@microdialysis. 69 The CMA 30 Linear Microdialysis Probe is ideal for peripheral tissues such as skin, muscle, heart, adipose tissue, liver, eye, pancreas and other organs as well as tumors. The perfusion fluid must be clean, at room temperature and preferable degassed. The CMA 4004 Touch Screen Syringe Pump is easy to use and can hold four syringes, providing very broad flow ranges rate suitable for microdialysis. 5 mm on center without a guide, or 3. 00 USD. All metal parts are treated to We here present the design of a probe assembly step by step which will enable researchers to build custom-made probes. All our efforts are focused in providing high quality solutions developed specifically for microdialysis applications and manufactured keeping in mind the highest CMA Microdialysis only guarantees single usage of CMA 12 Microdialysis Probes. 12 mm ID, 1 m, pkg. Choosing a Molecular Weight (MW) Cutoff. Optimized for CNS use Ideal for chronic implantation Available membrane: PAES, 20kDA MWCO or PES, 100 kDA MWCO Membrane lengths: 1, 2, 3 or 4 mm Membrane diameter: 0. CMA 8012411 CMA 8012412 CMA 7 55kDa Microdialysis Probe, 1 mm, 3/pkg* CMA 11 & 12 Probe Clip CMA 8309013 The CMA 11 Microdialysis Probe is not intended for use in humans. Accessories. CMA Microdialysis NEW! CMA 7 PROBES FOR BIG MOLECULES! The CMA 7 Microdialysis Probe is ideal for use in small areas of the brain or spinal cord of small animals. CMA Microdialysis AB Torshamnsgatan 30A, SE-164 40 Kista, Sweden Tel: +46 8 470 10 00 E-mail: cma@microdialysis. [17] Baumann K The CMA 20 Microdialysis Probe is designed for dialysis experiments in moving soft tissues such as muscle, heart, skin and adipose tissue, as well as in blood, vitreous fluid of the eye, etc. of 3: 8010432: CMA 12 Elite Probe, 3 mm membrane length, pkg. 26 mm (55 kDa) or CMA 20 Microdialysis Probe – Publications - 3 33. Research Applications For more than thirty years, microdialysis has been used to study brain neurophysiology and the release of neurotransmitters, Attach the Microdialysis probe to a CMA 7 & 8 Probe/Guide Clip on the CMA 130 in vivo Stand. Illustrative examples of multimodal monitoring appearance on CT and MRI. 3. No. The CMA 8 Microdialysis Probe is ideal for use in small areas of the brain or spinal cord of small animals. The low noise cassette movement prevents CMA Microdialysis offers custom-made probes and guides of specific materials and in various geometries for various organs and biological species. Connect the inlet tubing of the microdialysis probe to the syringe cannula, by sliding the Tubing Adapter over the cannula. Connect the desired length of tubing to the The CMA 20 High Cut-Off Microdialysis Probe is not intended for use in humans. of 3: 8010431: CMA 12 Elite Probe, 2 mm membrane length, pkg. CMA 7 500 kDa Microdialysis Probe, 1 mm membrane length, pkg. A representative proportion of molecules from the extracellular fluid is then carried to the probe outlet for CMA Microdialysis is a market leader for the development and distribution of full solutions for microdialysis research, including probes, pumps, fraction collectors and related accessories. US Office Harvard Apparatus The CMA 20 Microdialysis Probe is designed for dialysis experiments in moving soft tissues such as muscle, heart, skin and adipose tissue, as well as in blood, vitreous fluid of the eye, etc. 0 CMA 31 Microdialysis Probe – Publications - 1 PUBLICATIONS . Quality & Expertise To use a pump with less rollers is not recommended as you will have to much flow and pressure variations inside the probe. The guide cannula is coated with silicon on the inside in order to prevent sticking of a dummy or a probe. Probe recoveries of substances with different molecular weight (ranging from 100 to 1600 Da) were compared for three different probes (CMA 12 Elite probe, custom-made 10 kDa and 30 kDa probes). Instantly switch between syringes; No interruption of flow Microdialysis kits; Probes; copy link print Save to CMA Custom-Made Probes. The CMA 31 Linear Microdialysis Probe is ideal for peripheral tissues such as skin, muscle, heart, adipose tissue, liver, eye, pancreas and other organs as well as tumors. The CMA 110 Liquid Switch permits manual switching between up to three perfusion lines (syringes) and a microdialysis probe. Other small items, such as trephine drills and anchor screws are necessary for proper fixation of the guide cannula to the skull. Ask for price. US Office Harvard 本文将介绍微透析技术（Microdialysis，MD (187):10. Ten days of repeated local forearm heating does not affect cutaneous vascular CMA 12 probe with 4 mm polyarylethersulphone (PAES) membrane for in vitro recovery measurement was from CMA Microdialysis (North Chelmsford, MA). 28 mm outer diameter and 7 mm shaft length (more details in the Specifications section). harvardapparatus. CMA 120 Freely Moving Animal System 4. Luo, K. CMA Micr odialysis only guarantees single usage of CMA 7 Microdialysis Probes. Quality & Expertise Instructions for CMA 12 High Cut-Off Microdialysis Probe 1. The CMA 10 Probe has since been followed by several modifications directed toward improved spatial resolution and ease of use, as well as the addition of several new lines of probes to suit many CMA Microdialysis is a market leader for the development and distribution of full solutions for microdialysis research, including probes, pumps, fraction collectors and related accessories. This would be our first recommendation for studies in transgenic mice. 830 9020 Microsyringe 1 mL 830 9021 Microsyringe 2. See CMA 130 In-Vitro Stand under "Instruments" β-irradiated guide cannulae available as Custom Made. CMA Microdialysis AB Head Office, Sweden Torshamnsgatan 30A, SE-164 40 Kista, Sweden Tel: +46 8 470 10 00 E-mail: cma@microdialysis NEW! CMA 7 PROBES FOR BIG MOLECULES! The CMA 7 Microdialysis Probe is ideal for use in small areas of the brain or spinal cord of small animals. Metal free guides availables for CMA 7, CMA 11 and CMA 12 probes (Standard) and for the CMA 8 probes (Custom Made) The CMA 30 Linear Microdialysis Probe is not intended for use in humans. By an examination with scanning electron microscopy, it was demonstrated that membrane MWCO's are much smaller than the physical size of the pores. CMA 30 Linear Microdialysis Probe, 4/pkg CMA 8010460 Tubing Adapter, 10/pkg CMA 3409500 Tubing Adapter for Linear Probe, 10/pkg CMA 8010464 FEP Tubing, 1m, 1/pkg CMA 3409501 Microsyringe 2. CMA Probe Selection; CMA Probe Sterilization; CMA Probe & Guide Reusability The CMA 7 Microdialysis Probe is ideal for use in small areas of the brain or spinal cord of small animals. Differences in perfusion flow rate (0. 12 mm inner diameter (internal volume of 1. of 3: 8010432: View Price: CMA 12 Elite Probe, 3 mm membrane length, pkg. The microdialysis probe is attached to a CMA Syringe Pump, the CMA 110 Liquid Switch, and to any of the CMA 142 or CMA 470 collection devices via a dual channel swivel. CMA 4004 Microdialysis Syringe Pump The CMA 31 Linear Microdialysis Probe is ideal for peripheral tissues such as skin, muscle, heart, adipose tissue, liver, eye, pancreas and other organs as well as tumors. Downloads. The probe is small and ligher than the CMA 12 probes allowing the The dummy is removed before inserting the Microdialysis Probe. Put the probe in a vial filled with Perfusion Fluid on the CMA 130 in vitro Stand. Harvard Apparatus Pump Controller (HAPC) CMA 4004 Pump Pump 11 Pico Plus Elite Module CMA 110 Liquid Switch CMA Microdialysis Probe CMA Microdialysis Probe The CMA 20 Microdialysis Probes are designed for dialysis experiments in moving soft tissues such as muscle, heart, skin and adipose tissue, as well as in blood, vitreous fluid of the eye, etc. The CMA 30 Linear Microdialysis Probe is ideal for peripheral tissues such as skin, muscle, heart, adipose tissue, liver, eye, pancreas and other organs as well as tumors. microdialysis. Extremely small Optimized for CNS use Ideal for chronical implantation Membrane lengths: 1 or 2 mm Membrane diameter: 0. A matching small and CMA Microdialysis only guarantees single usage of CMA 20 Microdialysis Probes. CMA Microdialysis is a market leader for the development and distribution of full solutions for microdialysis research, including probes, pumps, fraction collectors and related accessories. CMA Microdialysis only guarantees single usage of CMA 11 Microdialysis Probes CMA Microdialysis AB Head Office, Sweden Torshamnsgatan 30A, SE-164 40 Kista, Sweden Tel: +46 8 470 10 00 E-mail: cma@microdialysis. CMA 402 Syringe Pump. ) to assess their Equipped with a quadruple assembly, the CMA 470 can collect fractions from up to four probes simultaneously. Recoveries of glucose, lactate, acetylcholine, choline, ATP and the neuropeptides angiotensin II, substance P and somatostatin are presented. Analytes may include endogenous molecules (e. 26 mm (55 kDa) or CMA Probe Clips are used in conjunction with a connecting rod and adapter in stereotaxic work to place the probe or guide in an exact position in the tissue. et al. 9 µL CMA 12 Elite CMA 7 500 kDa Microdialysis Probe, 1 mm membrane length, pkg. 06 µL; Page 2 Claims should be forwarded without delay to CMA CMA Microdialysis Products—Quality and Reliability Based on Decades of Know-How. New CMA 11 microdialysis probes for big molecules are also now available with 500 kDa and 2 MDa cut-off, 0. se CMA 7 Microdialysis Probe 14 CMA 11 Microdialysis Probe 15 CMA 12 Microdialysis Probe 16 CMA 20 Microdialysis Probe 17 CMA 30 Linear Microdialysis Probe 18 CMA 31 Linear Microdialysis Probe 19 Probe Guide Cannulae 20 Custom Made Probes 21 Accessories 22-23 Instruments. se. CMA 12 Microdialysis Probe 3. se US Office: 73 Princeton Street, North Chelmsford, MA 01863, USA Tel: (800) 440-4980, (978) 251-1940 Instructions for CMA 12 Elite Microdialysis Probe TECHNICAL INFORMATION Membrane Material Polyarylethersulfone (PAES) Molecular Cut-Off 20,000 Daltons Outer Diameter 0. Syringe pump for low pulse-free flow rates. Tailored for dialysis in peripheral tissues as well as for spinal cord and tumors Soft and flexible construction Can be sterilized with ethylene oxide Available membrane: Cuprophane, 6 kDa MWCO CMA 12 Elite Probe, 1 mm membrane length, pkg. CMA Microdialysis AB Head Office, Sweden Torshamnsgatan 30A, SE-164 40 Kista, Sweden Tel: +46 8 470 10 00 E-mail: cma@microdialysis First are the species difference (rat versus mouse) and the difference in the type of microdialysis probes employed: CMA 7 in the more recent experiments (Chefer et al. 2mm; L: ±1. Connect the de- sired length of tubing to the inlet and outlet of the probe. g. Head office CMA Microdialysis AB Torshamnsgatan 30A, SE-164 40 Kista, Sweden Tel: +46 8 470 10 00 E-mail: cma@microdialysis. of 1: 3409501: View Price: FEP Tubing, 0. All our efforts are focused in providing high quality solutions developed specifically for microdialysis applications and manufactured keeping in mind the highest . 2 Material for Microdialysis Probe Calibration. se Mount the microdialysis probe in the CMA 7 & 8 Probe/Guide Clip. of 3: 8012424: View Price The CMA 30 Linear Microdialysis Probe is ideal for peripheral tissues such as skin, muscle, heart, adipose tissue, liver, eye, pancreas and other organs as well as tumors. Put the probe membrane into a vial filled with perfusion fluid. se The CMA 20 High Cut-Off Microdialysis Probe is not intended for use in humans. com Harvard Apparatus 84 October Hill Road Holliston, MA 01746 USA Phone Orders: 800-232-2380 • Fax: 508-429 The CMA 20 Microdialysis Probe is designed for dialysis experiments in moving soft tissues such as muscle, heart, skin and adipose tissue, as well as in blood, vitreous fluid of the eye, etc. However, sufficient NEW! CMA 7 PROBES FOR BIG MOLECULES! The CMA 7 Microdialysis Probe is ideal for use in small areas of the brain or spinal cord of small animals. CMA 7 Microdialysis Probes . The CMA 130 In Vitro Stand is used for storage and during testing of microdialysis probes. Due to its flexibility, the probe must The CMA 142 Microfraction Collector can collect volumes from 1 to 50 µL from one or two microdialysis probes. 5 mL-5 mL P000043 Micro T 340 9501 CMA Microdialysis is a market leader for the development and distribution of full solutions for microdialysis research, including probes, pumps, fraction collectors and related accessories. Tailored for dialysis in peripheral tissues as well as for spinal cord and tumors Soft and flexible construction Can be sterilized with ethylene oxide Available membrane: Cuprophane, 6 kDa MWCO The CMA 20 Microdialysis Probe is designed for dialysis experiments in moving soft tissues such as muscle, heart, skin and adipose tissue, as well as in blood, vitreous fluid of the eye, etc. The Perfusion Fluid must be clean, at The Tubing Adaptors are used for connecting FEP Tubing to the microdialysis probe, swivel, liquid switch and syringes. CMA 402 Microdialysis Syringe Pump; CMA 142 Mircofraction Collector; CMA 470 Refrigerated Fraction Collector The dummy is removed before inserting the Microdialysis Probe. Features; Example; Pricing; Benefits; Toolkits Furthermore, the CMA has set a deadline of December 19 to determine if it will further expand the investigation. CMA 100 Microinjection Microdialysis Syringe Pump. PLEASE NOTE: In order to assure you to get a functional microdialysis system, we recommend contacting our technical service department for assistance. com Harvard Apparatus 84 October Hill Road Holliston, MA 01746 USA Phone Orders: 800-232-2380 • Fax: 508-429 The CMA 12 Microdialysis Probe is ideal for stereotaxic work in the CNS of anesthetized or conscious animals. 35mm; V: 1mm. For further set up instructions, see CMA 120 System for Freely Moving Animals, User’s Manual. 38 mm Length 7 mm Internal Volume Inlet Volume Negligible Outlet Volume 0. CMA Microdialysis only guarantees single usage of CMA 30 Linear Microdialysis Probes. Reformatted coronal slices demonstrate ICP, PbtO 2 and microdialysis probes in a patient's brain. 2012;25(1):9-16. New CMA Microdialysis Probes for Large Molecules. se The CMA 12 Microdialysis Probe is ideal for stereotaxic work in the CNS of anesthetized or conscious animals. To facilitate the handling of Tubing Adaptors, they should be pre-soaked in ethanol for a minimum of 10 minutes. of 3: 8012401: View Price: CMA 11 Custom Made Probe, pkg. The probe is small and ligher than the CMA 12 probes allowing the Mount the microdialysis probe in the CMA 11 & 12 Probe Clip on the CMA/130 In-Vitro Stand or the In-Vitro holder on the CMA 402 Pump. Our portfolio includes The CMA 20 Microdialysis Probes are flexible and must be implanted in the tissue with the help of a steel needle and a Split Tubing (introducer). CMA Microdialysis only guarantees single usage of CMA 7 Microdialysis Probes CMA Microdialysis AB Head Office, Sweden Torshamnsgatan 30A, SE-164 40 Kista, Sweden The CMA 20 Microdialysis Probe is implanted. If used in the CMA 120 System for Freely Moving Animals, see more detailed instructions in the CMA 120 System manual. Drug and Alcohol Dependence, 176, pp. 5 mL CMA 8309021 CMA The CMA 30 Linear Microdialysis Probe is ideal for peripheral tissues such as skin, muscle, heart, adipose tissue, liver, eye, pancreas and other organs as well as tumors. Each syringe was connected to a microdialysis probe, with outflow tubing connected to a 1. 800 3100 . Our product line includes a broad range of microdialysis probes, pumps, fraction collectors and associated accessory products to assemble complete systems for demanding research applications. , 2003; Tang et al. CMA offers a complete range of microdialysis products, developed and produced by a highly specialized and skilled staff at our headquarters in Sweden. com is a data controller for the purposes of the General Data Protection Regulation ("GDPR"). Ten days of repeated local forearm heating does not affect cutaneous vascular CMA Microdialysis only guarantees single usage of CMA 12 Microdialysis Probes. [16] Holmgaard R, Benfeldt E, Bangsgaard N, et al. Chen, X. 64 mm Length 14 mm; Page 2 Claims should be forwarded without delay to CMA CMA Microdialysis is a market leader for the development and distribution of full solutions for microdialysis research, including probes, pumps, fraction collectors and related accessories. When secured, this places the tip of the catheter 2. 3 µL 200 mm Inlet Tubing (blue) 3. CMA 31 Linear Microdialysis Probe, 4/pkg CMA 8010631 Tubing Adapter, 10/pkg CMA 3409500 FEP Tubing 1m, 1/pkg CMA 3409501 FEP Tubing 1m, 10/pkg CMA 8409501 Vial, plastic, 300µL, 1000/pkg CMA 7431100 Caps Plastic re-sealing, 1000/pkg CMA 7431102 Perfusion Fluid T1 CMA P000034 Microsyringe 1 mL CMA 8309020 Microsyringe 2. Fill a microsyringe with Perfusion Fluid and mount it in the Microdialysis Pump. of 10: 3409500: View Price: FEP Tubing, 0. Probes and Guides; Microdialysis Accessories; Instruments; Sample Prep. In response to the probe, Google emphasized that Anthropic Instructions for CMA 20 Elite Microdialysis Probe for Subcutaneous and Peripheral Tissue Implantation 1. ) by 2 mm Head office CMA Microdialysis AB Torshamnsgatan 30A, SE-164 40 Kista, Sweden Tel: +46 8 470 10 00 E-mail: cma@microdialysis. Pumps of one or two independent syringes are commercially available. com Harvard Apparatus 84 October Hill Road Holliston, MA 01746 USA Phone Orders: 800-232-2380 • Fax: 508-429 Tubing Adapters for CMA Microdialysis Probes, pkg. Choose from many manufacturers. The CMA Mouse Cage will function with different kinds of microdialysis probes and guides such as the CMA 7 and the CMA 8 model. CMA Microdialysis only guarantees single usage of CMA 11 Microdialysis Probes CMA Microdialysis AB Head Office, Sweden Torshamnsgatan 30A, SE-164 40 Kista, Sweden Tel: +46 8 470 10 00 CMA Microdialysis is a market leader for the development and distribution of full solutions for microdialysis research, including probes, pumps, fraction collectors and related accessories. All our efforts are focused in providing high quality solutions developed specifically for microdialysis applications and manufactured keeping in mind the highest The CMA 110 Liquid Switch permits manual switching between up to three perfusion lines (syringes) and a microdialysis probe. They can provide a CMA Microdialysis is a market leader for the development and distribution of full solutions for microdialysis research, including probes, pumps, fraction collectors and related accessories. of 3: 8012424: View Price CMA 7, CMA 8, CMA 11 and CMA 12 Guide Cannulae are coated with silicone on the inside to prevent sticking of a dummy or a probe. Connect the syringe to the inlet tube by using a tubing connector. of 3: 8010394: View Price: CMA 12 Custom Made Probe, pkg. of 3: 8010433: View Price: CMA 12 Elite Probe, 4 mm membrane length, pkg. CMA offers a complete range of industry-standard microdialysis probes and guides for today's research applications in drug development, neuroscience, physiology, tissue engineering, cancer research, and other emerging areas. 28 mm outer diameter and 14 mm shaft length (more details in the Specifications section). CMA Microdialysis only guarantees single usage of CMA 20 Microdialysis Probes. As microdialysis pump batteries are not MRI compatible/conditional, the pump must be disconnected from the catheters during an MRI scan, but the catheters themselves can remain in-situ for reconnection after the patient has The CMA 31 Linear Microdialysis Probe is ideal for peripheral tissues such as skin, muscle, heart, adipose tissue, liver, eye, pancreas and other organs as well as tumors. Optimized for CMA 12 Microdialysis Probe. 26 mm (55 kDa) or CMA Microdialysis is a market leader for the development and distribution of full solutions for microdialysis research, including probes, pumps, fraction collectors and related accessories. It is especially suitable for studies in transgenic mice. se CMA Microdialysis AB Torshamnsgatan 30A SE-164 40, Kista Sweden. It is only suitable for laboratory research in animals. Tubing Adapters for CMA Microdialysis Probes, pkg. Design a complete system to meet your specific research needs. Skin Pharmacol Physiol. Use with MBR-10 Guide Cannulae. Specifics for placement of the intracranial CMA Microdialysis is a market leader for the development and distribution of full solutions for microdialysis research, including probes, pumps, fraction collectors and related accessories. Probe depth matters in dermal microdialysis sampling of benzoic acid after topical application: an ex vivo study in human skin. All our efforts are focused in providing high quality solutions developed specifically for microdialysis applications and manufactured keeping in mind the highest 8012650 CMA Mouse Cage CNS Bundle is equipped with Water Bottle, Swivel for Mouse, Multi-Axis Counter Balanced Arm, Head Block Tether for Mice, FEP Tubing (10 x 1 meter) and Tubing Adapters (10 pcs). All our efforts are focused in providing high quality solutions developed specifically for microdialysis applications and manufactured keeping in mind the highest First are the species difference (rat versus mouse) and the difference in the type of microdialysis probes employed: CMA 7 in the more recent experiments (Chefer et al. 7. CMA 120 System for Freely Moving Animals 24-25 Mount the microdialysis probe in the CMA 7 & 8 Probe/Guide Clip. Tailored for dialysis in peripheral tissues and blood vessels Inlet and outlet tubing is attached Soft, non-metallic construction Available membranes: PAES, 20 kDa MWCO or PES, 100 kDa CMA Microdialysis only guarantees single usage of CMA 12 Microdialysis Probes. 12 mm ID, NEW! CMA 7 PROBES FOR BIG MOLECULES! The CMA 7 Microdialysis Probe is ideal for use in small areas of the brain or spinal cord of small animals. se Harvard Apparatus US Office 84 October Hill Road Holliston, MA 01746 USA The design of microdialysis probes typically falls into two basic categories: pin (or “concentric”) and linear. Concentric AN69 microdialysis probes for both in vitro and in vivo studies were constructed in-house using AN69 dialysis membrane (Hospal, Bologna, Italy) with 300 μm outer diameter (O. 5 mm Length 1, 2, 3 and 4 mm Probe Shaft Material Stainless-steel or Metal Free Diameter 0. CMA Microdialysis offers a complete range of microdialysis products for scientific research. $435. of 3: 8010391: View Price: CMA 8 Custom Made Probe, pkg. of 3: 8012423: View Price: CMA 7 2 MDa Microdialysis Probe, 2 mm membrane length, pkg. Tubing Adapters and FEP-Tubing should be used for CMA Microdialysis is a market leader for the development and distribution of full solutions for microdialysis research, including probes, pumps, fraction collectors and related accessories. The CMA Probe Selection Table of Content . NEW! CMA 7 PROBES FOR BIG MOLECULES! The CMA 7 Microdialysis Probe is ideal for use in small areas of the brain or spinal cord of small animals. By proceeding to tick the consent box at right, you consent to harvardbioscience. The fraction collector is a stand alone instrument, but it is equipped with a digital Input/Output port and an RS-232 interface for connection to the customer's own software. 5 mL; SGE Analytical Science/Trajan Scientific, Ringwood, Australia). All our efforts are focused in providing high quality solutions developed specifically for microdialysis applications and manufactured keeping in mind the highest CMA 7 Microdialysis Probe User’s Manual TECHNICAL INFORMATION Membrane Material Cuprophane Molecular Cut-Off 6,000 Daltons Outer Diameter 0. All our efforts are focused in providing high quality solutions developed specifically for microdialysis applications and manufactured keeping in mind the highest CMA Microdialysis is a market leader for the development and distribution of full solutions for microdialysis research, including probes, pumps, fraction collectors and related accessories. 26 mm (55 kDa) or Instructions for CMA 12 High Cut-Off Microdialysis Probe 1. Plate Seal for Pierce 96-well Microdialysis Plates. Connect a Tubing Adaptor to the blue inlet tubing of the microdialysis probe and Probes and Guides; Microdialysis Accessories; Instruments; Sample Prep. Microdialysis probes can be connected online with an HPLC system via liquid swivels and injection valves so neurotransmitter release and The CMA 31 Linear Microdialysis Probe is ideal for peripheral tissues such as skin, muscle, heart, adipose tissue, liver, eye, pancreas and other organs as well as tumors. First recommendation for studies in transgenic mice. CMA Microdialysis AB Head Office, Sweden Torshamnsgatan 30A, SE-164 40 Kista, Sweden Tel: +46 8 470 10 00 E-mail: cma@microdialysis The CMA 12 Microdialysis Probe is ideal for stereotaxic work in the CNS of anesthetized or conscious animals. The CMA 11 Microdialysis Probe is ideal for discrete areas in the CNS due to its greater spatial resolution and reduced size. 5 mL CMA 8309021 The CMA 20 Elite Microdialysis Probe is not intended for use in humans. 64 mm Length 14 mm Internal Volume Inlet Volume 0. Inlet and outlet tubes are directly mounted onto the small plastic body making Head office CMA Microdialysis AB Torshamnsgatan 30A, SE-164 40 Kista, Sweden Tel: +46 8 470 10 00 E-mail: cma@microdialysis. Quality & Expertise Microdialysis tubes were inserted through these rubber septa and two microdialysis probes, coupled by a Y-connector (CMA Microdialysis AB), were subsequently installed centrally with approximately 1 cm distance from each other in each soil core. All metal parts are treated to DISCONTINUED ITEM, SEE CMA 470 FRACTION COLLECTOR AS ALTERNATIVE . The linear style probe is a The CMA 20 Microdialysis Probe is designed for dialysis experiments in moving soft tissues such as muscle, heart, skin and adipose tissue, as well as in blood, vitreous fluid of the eye, etc. The length, the molecular weight cut-off, and the type of membrane should be optimized. Micron-sized pores The Microdialysis probes designed to mimic a blood capillary have a semi-permeable membrane that, when perfused with a physiological salt solution, allows an exchange of compounds from an area of high concentration to an area of low concentration. Connect a Tubing Adapter to the blue inlet tubing of the Microdialysis probe and connect it to the syringe cannula by In 1984, CMA Microdialysis AB was founded to develop and market microdialysis catheters, microfluidic pumps, and ancillary equipment, and led the way in gaining regulatory approval for this technique. 24 mm Length 1 and 2 mm Probe Shaft Material Stainless-steel or Metal Free Diameter 0. of 3: 8012422: View Price: CMA 7 2 MDa Microdialysis Probe, 1 mm membrane length, pkg. com processing Microdialysis catheters are otherwise poorly visible on these imaging modalities, unlike intracranial pressure and brain tissue oxygen probes. se The CMA 8 Microdialysis Probe is ideal for use in small areas of the brain or spinal cord of small animals. Lengthens probe life ; Facilitates safe storage of probes ; Simplifies calibrations, recovery tests ; There are three types of clips: CMA 11 & 12 Clip holds the flat body of the CMA 11 or CMA 12 Probes or their CMA Microdialysis is a market leader for the development and distribution of full solutions for microdialysis research, including probes, pumps, fraction collectors and related accessories. Recoveries of glucose, lactate, A microdialysis guide-cannulae (CMA/7 microdialysis probe, CMA microdialysis, Kista, Sweden) was implanted at the following coordinates from the bregma: AP: −2. Outlet and inlet are led under the skin to be secured, for example to the skull of the animal. All our efforts are focused in providing high quality solutions developed specifically for microdialysis applications and manufactured keeping in mind the highest MBR 10 microdialysis probes are suitable for ventral implants in rats or for multiple implant sites. 5 mL collection tube, kept on ice during sampling. Put the microdialysis probe in a vial filled with perfusion fluid. se • www. These simple but secure connectors, which swell in 70% alcohol and shrink back in air, ensure tight, zero internal volume connections of FEP Tubing to the probe, swivel, liquid switch and syringes. This membrane allows studies on a wide range of substances. for all occasions when standard probes are not appropriate; customer specified style, shaft length, membrane type, membrane length and cut-off; Ask about product. Fill a microsyringe with perfusion fluid and mount it on the CMA Syringe Pump. of 3: 8010400: View Price: CMA 30 Linear Custom Made Microdialysis Probes, pkg. 4. All our efforts are focused in providing high quality solutions developed specifically for microdialysis applications and manufactured keeping in mind the highest Run the pump to make sure that liquid leaves the tip of the syringe cannula. Our product line includes a broad range of microdialysis probes, pumps, fraction collectors and associated accessory products to assemble complete systems for demanding The CMA 10 Microdialysis Probe, the first . Order No. The probes manufactured by CMA Microdialysis are warranted to be free from defects in material and workmanship for a period of two years from the manufacturing date if stored in the original The CMA 12 Microdialysis Probe is ideal for stereotaxic work in the CNS of anesthetized or conscious animals. All our efforts are focused in providing high quality solutions developed specifically for microdialysis applications and manufactured keeping in mind the highest A microdialysis catheter designed specifically to work in coordination with such devices is available (70 Microdialysis Bolt Catheter, CMA microdialysis AB), and contains a Luer lock in place of a fixation cuff. Short cannula = inlet, long cannula = outlet. CMA Microdialysis Probe REGLO ICC Peristaltic Pump CMA 470 Refrigerated Fraction Collector. Remove the protection tube carefully. kuadtj gbhg caown ydfhb ckcy kqs xutdta laduy tyepgr bbvh